Hepatocellular carcinoma (HCC) is a highly heterogeneous malignancy characterized by marked cellular and spatial diversity within the tumor microenvironment (TME). The transforming growth factor-β ...

Abstract: Spatial transcriptomics has revolutionized the ability to investigate transcriptional patterns within tissue morphology. However, many ST clustering pipelines operate on a single preselected ...

Foster City, Calif. | January 27, 2026 — Signios Bio today announced the launch of a new grant program supporting innovative spatial transcriptomics research using the 10x Genomics Xenium 5K Spatial ...

Advancements in spatial perturbation transcriptomics (SPT) have revolutionized our understanding of cellular behavior in native tissue contexts by integrating spatial and perturbation data. However, ...

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

Abstract: Spatial transcriptomics technology enables researchers to acquire both spatial location information and gene expression data within tissues, providing new perspectives for understanding ...

(MEMPHIS, Tenn. – December 3, 2025) Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located. However, the rapid growth of the technology ...

Understanding the temporal dynamics of gene expression within spatial contexts is essential for deciphering cellular differentiation. RNA velocity, which estimates the future state of gene expression ...

Background: Lung tissue exhibits intricate spatial organization and dynamic cellular interactions. However, the molecular mechanisms underlying pulmonary arterial hypertension (PAH) remain poorly ...

Experiments were executed with PyTorch 2.1.0+cu121 on NVIDIA A40 with 46068MiB memory in linux environment. adata_utils file contains 4 functions, preprocess function selects highly variable genes ...