The discovery of Hoogsteen base pairs, an alternative pairing mode to the canonical Watson–Crick structure, has significantly broadened our understanding of DNA dynamics. This conformation, in which ...

Artificial DNA letters beyond A, T, G, C break a fundamental pairing rule to produce nanostructures with new shapes, far greater durability, and an unexpected ability to self-sort.

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases. (Image: Wikimedia Commons, CC SA 3.0) The most common type of base pairing is the Watson-Crick base ...

For the first time, researchers have succeeded in developing an artificial DNA base pair that is based on a different chemical force than natural genetic material. While the common natural DNA ...

DNA is the genetic material used by every living organism. But, in a few edge cases, the four bases of DNA—adenine, thymidine, cytosine, and guanine—undergo chemical modifications. And in viruses, ...